Coming Together for a Cure
Pediatric Cancer Foundation is a 501(c)(3) nonprofit organization. Our mission is to fund groundbreaking research and early phase clinical trials to eradicate childhood cancer.

- #1
- Cancer is the #1 cause of non-accidental death in children under 20
- 1 in 260
- 1 in 260 children will develop cancer before their 20th birthday
- 100+
- There are over 100 subtypes of pediatric cancers
- 11.1M
- 11.1 million children will die before the year 2050 if we stop investing in research
Why We Exist
We fund the sciencethat gives childrenmore tomorrows.
What we fund
Groundbreaking research and early-phase clinical trials across the full spectrum of pediatric cancers, including rare and overlooked diseases.
How projects are selected
A volunteer Medical Advisory Board of leading physicians evaluates every proposal against a rigorous, multi-faceted scoring process.
Why early funding matters
Early support carries promising science across the hardest gap, from laboratory discovery toward trials for children.
Why donors trust PCF
Over 55 years of relationship-based fundraising, disciplined expenditure, and strategic allocation — with published financials and independent Candid transparency.
Every gift follows the same disciplined path.
Your donation
Individuals, family foundations and corporations fund the work. PCF receives no federal funding.
Expert review
The Medical Advisory Board scores each proposal against a rigorous rubric.
Research
Only the highest rated projects at leading institutions are funded.
Early trial or discovery
Support can help move promising discoveries toward early-phase clinical trials.
Progress for children
Researchers work toward safer, more effective options for children who cannot wait.
Featured Research

Alice Lee, MD
Pediatric hematology-oncology
Montefiore Medical Center · Bronx, NY
Pediatric Early-Phase Clinical Trials Program
Expanding early-phase trial access for underserved children
The Pediatric Oncology Early Phase Clinical Trial Program (PEPCTP) focuses on patients with relapsed/refractory disease who are unable to access novel oncology therapies, in an underserved and under-resourced patient population.
Why it matters: The program has grown to offer many studies and new therapies to children whose cancers are difficult to treat.
PCF support helps sustain the program’s trial infrastructure and expand access close to home.
Get loud!
Less than 4 percentIs not enough
Less than 4% of all federal cancer research funding is allocated to children.
A network of the institutions defining pediatric oncology.
PCF's Developmental Therapeutics Program at Columbia University develops and tests novel treatments for children with incurable cancer — from target discovery to clinical trials.
- Children's Hospital of PhiladelphiaPhiladelphia, PA
- Memorial Sloan Kettering Cancer CenterNew York, NY
- Columbia University College of Physicians & SurgeonsNew York, NY
- Montefiore Medical CenterBronx, NY
- Icahn School of Medicine at Mount SinaiNew York, NY
- NYU Grossman School of MedicineNew York, NY
- NYU Langone HealthNew York, NY
- New York Medical CollegeValhalla, NY
- Children's Hospital Los AngelesLos Angeles, CA
- The Ohio State University Comprehensive Cancer CenterColumbus, OH
- University of Michigan Medical SchoolAnn Arbor, MI
- Johns Hopkins UniversityBaltimore, MD
- University of PittsburghPittsburgh, PA
- UT Health San AntonioSan Antonio, TX
As seen on CNBC
Empowered, featuring Meg Ryan
PCF’s work was featured in the CNBC “Empowered” series.
Support Our Mission
Choose how you’ll move the science forward.
Tribute Memorial Gifts
Dedicate your Donation.
Make a tribute giftDonor Advised Funds (DAF)
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DAF DIRECTAttend an Event
Join PCF at our Annual Benefit and other community events.
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Bring your own idea and community together to fund research.
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Partner as an organization with measurable return.
Explore corporate partnershipsThe urgency
The next breakthrough is waiting on funding, not on time.
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